A 34-year-old man presents to your office for follow up on lab results which were completed to evaluate an elevated AST and ALT. He is sexually active and engages in sex with both men and women. He uses condoms inconsistently. He denies regular alcohol abuse but states he used to inject heroin. Currently, he reports some fatigue but says he feels well otherwise. His hepatitis serology results are as follows: HBsAg-positive, anti-HBs-negative, and anti- HBc-positive IgG, Anti-HDV and anti-HCV test results are both negative.
A 34-year-old man presents to your office for follow up on lab results which were completed to evaluate an elevated AST and ALT. He is sexually active and engages in sex with both men and women. He uses condoms inconsistently. He denies regular alcohol abuse but states he used to inject heroin. Currently, he reports some fatigue but says he feels well otherwise. His hepatitis serology results are as follows: HBsAg-positive, anti-HBs-negative, and anti- HBc-positive IgG, Anti-HDV and anti-HCV test results are both negative.
Questions
1. The clinical scenario is most consistent with which diagnosis?
2. What data in the clinical scenario supports your diagnosis?
3. What are this patient’s risk factors for acquiring the disorder identified in question 1?
4. Describe the key pathophysiologic concepts of the diagnosis in question 1.
5. For what actual or potential complications related to the diagnosis in question 1 does he need to be monitored?
a. What would a positive serology test indicate for each test below?
Hepatitis A IgM (HAV-Ab/IgM) | |
Hepatitis A IgG (HAV-Ab/IgG) | |
Hepatitis B Surface Antigen (HBsAg) | |
Hepatitis B Surface Antibody (HBsAb or Anti-HBs) | |
Total Hepatitis B core antibody IgG
(HBcAb or anti-HBc) |
|
Hepatitis B core antibody IgM
(IgM anti-HBc) |
|
Hepatitis C Antibody
(HCV-Ab) |
|
HDV-Ab (Hepatitis D antibody IgM) | |
Total HDV-Ab |
b. What percentage of patients with the acute hepatitis B infection develop chronic HBV infection?
c. What is the significance of hepatitis D superinfection?
d. What two hepatitis B serologies must be present to diagnose an acute infection?
The post A 34-year-old man presents to your office for follow up on lab results which were completed to evaluate an elevated AST and ALT. He is sexually active and engages in sex with both men and women. He uses condoms inconsistently. He denies regular alcohol abuse but states he used to inject heroin. Currently, he reports some fatigue but says he feels well otherwise. His hepatitis serology results are as follows: HBsAg-positive, anti-HBs-negative, and anti- HBc-positive IgG, Anti-HDV and anti-HCV test results are both negative. appeared first on commompapers.org.
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