Question

A randomized trial is conducted to evaluate the efficacy of a new cholesterol lowering medication. The primary

outcome is incident coronary artery disease. Participants are free of coronary artery disease at the start of the study and randomized to receive either the new medication or a placebo. Participants are followed for a maximum of 10 years for the development of coronary artery disease.

The following data are:

                                                                     Number participants              Number with coronary artery disease

Cholesterol medication                                      400                                                      28

Placebo                                                                   400                                                     42

Compute the Relative Risk of coronary artery disease in patients receiving the new medication as compared to placebo.

       Relative Risk =

Compute the Odd ratio of coronary artery disease in patients receiving the new medications as compared to placebo

     Odds Ratio =

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