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Identify the type of legislation, such as state, federal, scope of practice, reimbursement, loan repayment, or others.

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The purpose of this assignment is for you to identify an issue of concern for your role as an advanced practice nurse and to formulate a potential policy change to address that issue. There are many potential issues which can influence your practice setting or other issue which may negatively affect the patients with whom you work. All of the course reading will help you to identify a topic for this assignment. You can think about the issue as related to your health promotion project. The policy you consider may be in reaction to the health promotion issue or something larger that is still related to that issue. There are hundreds of possible issues, but here is a list of a few to consider:
•Child and elder care
•Civil rights
•Domestic violence
•Drug abuse/addiction
•HIV/AIDS
•Homelessness
•Native American and migrant workers’ health
•Long-term care
•Immigration/illegal aliens
•Legislative issues affecting advanced practice nursing
•Barriers to practice
•Access to care

As you begin to work on the possible policy change: the following ideas and steps should be considered:
•Definition and description of the issue
•Exploration of the background of the issue
•Stakeholders
•Issue statement or statement of clarity
•Possible methods of addressing the issue
•Goals and options for changes
•Risks and benefits of the changes
•Evaluation methodology
•Recommendation or solution
Submit a Power Point presentation. This will include the notes pages to explain the content within each slide. Be sure to use APA style and include all of your references.

Grading Criteria
Maximum Points

Identify the type of legislation, such as state, federal, scope of practice, reimbursement, loan repayment, or others.
20

Review of the literature consists of a minimum of 3–4 peer-reviewed articles and 6–7 other outside sources.
30

Describe the current policy or health policy issue and specify how it would impact nursing or healthcare.

10

Describe the specific aspects of the proposed policy or policy change.
20

Identify the individuals who would benefit from the policy change and explain where support for the change would be found.
20

Describe the impact of the policy change on nursing practice and health care.
10

Provide an analysis of the policy from your point of view and how this will influence your practice.
20

Uses good writing skills, appropriate grammar, and application of APA formatting throughout paper, citations, and references.
10

Total:
140

 

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Describe, briefly, the challenges to the validity of study designs; relate these challenges to case-control studies, cohort studies, and randomized controlled trials.

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Give an example of a hypothetical ecologic study. Name and describe one advantage and one disadvantage of ecologic studies. [p. 110]
• Describe, briefly, the challenges to the validity of study designs; relate these challenges to case-control studies, cohort studies, and randomized controlled trials. [p. 117]
• Do you have a smokefree bars law in your community? What considerations led to the development of such laws in communities that have adopted them? What are three policy implications of smokefree bars laws? [pp. 130, 131]
• Explain what is meant by the risk management component of risk assessment. From your own experience, discuss how risk management applies to the regulation of pesticides for home use. [p. 130]
• Describe the components that make up the epidemiologic triangle. Indicate how these components could be implicated in an outbreak of foodborne illness (e.g., an illness outbreak caused by Salmonella-contaminated tomatoes). [p. 138]
• Give one argument for and one argument against the proposition that vaccine-preventable diseases represent a diminished hazard to society. [pp. 151, 152]
• Explain the trends of obesity in the United States over time. Compare the trends among children and teenagers versus adults. [pp. 171, 172]
• What is the triad of disorders reported for children with severe emotional or behavioral difficulties? Discuss the implications of these disorders for the social functioning of children. [p. 174]
• Describe two person characteristics that are associated with Down syndrome. In your own opinion and in light of these epidemiologic associations, what preventive measures could be taken? [p. 183]
• What is one of the major consequences of children’s exposure to environmental lead? Suggest two methods for reducing such exposure. [p. 185]

 

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Explore the Gene page for the underlying genomic DNA sequence as there is a large amount of basic information on this page relevant to the function and relationship with other proteins.

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The Protein Project will consist of 3 parts. If you have not selected your own protein then you will be assigned a protein for completion of the project. Literature references should be included with citations to the source of material.

Part A: Protein Description and History

Identify some of the basic structure and chemical features (AA sequence, MW, pI, etc.) of your protein using the information and tools on NCBI, ExPASy, Protein Data Bank, etc. websites. (See the Resources links below.)
Give an extensive literature based overview of your protein. From journal articles determine more about the history, functions, and possible roles in cellular mechanisms. Also, explore if this protein has been linked to diseases or disorders.

Part B: Understanding the Structure & Function

Develop a set of visuals (tables, charts, images, etc.) to convey the basic information of the protein identified above (MW, pI, hydrophobicity, etc.).
Give the complete amino acid sequence for protein
Give an image of the 3-D structure and identify secondary structural features
How do the elements of the protein structure influence the function of the protein? Are there elements that could be changed and not affect the function? What are the structural elements that are required for proper function?

Part C: Comparisons to Other Proteins and Species

Use the BLAST tool on the protein websites to compare you protein sequence to other proteins and species. If you use NCBI, you can control the species name to get only other proteins within that species or leave it blank to get proteins in all species.
From the BLAST data, create a phylogenetic tree of different proteins with the organism and one relating the same protein in different species.
Use the ClustalW link on one of the websites to develop an amino acid sequence comparison and present this comparison.
Explore the Gene page for the underlying genomic DNA sequence as there is a large amount of basic information on this page relevant to the function and relationship with other proteins.
Identify interactions with other proteins, activities within the cell or biological functions (Gene Onotology, Biosystems, Pathways, etc.).
From the HomoloGene page identify the protein motifs found with in your protein and the level of conservancy of this protein across species.
How does a deeper understanding of primary amino acid sequence and identification of specific sequence motifs help identify the protein structure and function? Expand on the similarity of this protein to other proteins and the level of conservancy across species. How can this knowledge improve our understanding of the function and history of this protein? What can you learn about functions from identifying interactions between this protein and other proteins?

Part D: Conclusion/Discussion of the Protein

Expand on the role of this protein in known cellular and organismal mechanisms. What are some known disorders or diseases caused by abnormal structure and function of this protein? Speculate on some possible changes in protein structure and function that have not been identified or confirmed yet and how that abnormal structure could affect the functions of this protein in some future disease.

 

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Critically compare alternative scenarios for the impact of climate change on patterns of water­related infectious disease in both developed and less­developed countries.

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Paper , Order, or Assignment Requirements Question 1 Explain using appropriate examples, how the environmental classification of excreta­related diseases may help engineers to meet the UN Millennium Development Goals for improved water supply and sanitation. Question 2 Critically evaluate the ways in which the human body is able to protect against infection by pathogenic organisms using ‘specific’ and ‘non­specific’ defences. Provide examples to support your answer. Question 3 Critically compare alternative scenarios for the impact of climate change on patterns of water­related infectious disease in both developed and less­developed countries.

 

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