How does bafilomycin work to block acidification of endosomes to prevent diphtheria toxicity?
How does bafilomycin work to block acidification of endosomes to prevent diphtheria toxicity?
Toxins acidify the endosome to function and hurt the host cell, but aren’t the functions of these endosomes to kill bacteria because of their high acid content? Why would the toxin want to stay in a toxic environment…