Autosmal DNA – Paternal Grandfather and A Grandson Paper

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Everything is below!

This project evaluates your understanding of the unique inheritance of autosomal DNA, the limitations of atDNA testing, and how atDNA is transmitted from one generation to the next.

The following is a comparison of the DNA of a paternal grandfather and a grandson on chromosome 1, where gray indicates the chromosome and brown indicates the shared segments of DNA:

Image of 1 line representing Chromosome 1. Within the line segment, it is grey, brown, grey, brown, grey.

On the basis of your understanding of autosomal DNA and this comparison, answer the following questions:

  1. Since this comparison is of a paternal grandfather and a grandson, it represents a single recombination. At least how many recombination events had to occur in order to observe this pattern?
  2. Based on the above comparison alone, can you determine the segments of DNA on chromosome 1 that the grandson received from his maternal grandmother? Why or why not?
  3. Let’s follow the same chromosome through to the next generation, to the grandson’s son, and compare it to the same paternal grandfather (now a great-grandfather). Could the comparison of the great-grandfather and great-grandson look like the result below? Why or why not?

Image of 1 line representing Chromosome 1. Within the line segment, it is grey, brown, grey, brown, grey, brown.

Hallie’s family tree is below. Amazingly, Hallie has tested all of her grandparents and five of her eight great-grandparents. Three of her great-grandparents, unfortunately, are deceased. Based on the results of the testing, Hallie has determined exactly how much DNA she obtained from the grandparents and great-grandparents that were tested, as shown in the table below.

Image of Hallie’s family tree.

Ancestor Shared Percentage
Grandparents John 24.0%
Jane 26.0%
Chris 20.0%
Cindy 30.0%
Great-grandparents Hugh 14.0%
Helen 10.0%
Philip DECEASED
Phyllis 15%
Thomas DECEASED
Theresa 10.0%
Morris DECEASED
Mary 17.0%
  1. Based on the family tree and the graph, what are the correct percentages for Philip, Thomas, and Morris? Adding all the great-grandparents’ percentages together, what is the total? At the great-grandparent level, do any of the percentages seem high or low compared to expected amounts. If so, which one(s)? Why or why not?

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explain what meant variance set obervations and then define standard deviation set obervatio

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Part of my math project help needed! Extra info: “Many standard statistical methods are intended for use with distributions that are symmetric and have no outliers. These methods start with the mean and the standard deviation.”

 

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on time please

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Assignment 1: Identifying Stages of Development

Post your response to the question below with at least 200 words in the Discussion Area by Saturday, March 4, 2017. Cite information from at least one academic source, such as your textbook or an article from the Argosy Online Library, to support your statements. Use current APA standards to properly cite your source(s). Review and respond to your classmates through Wednesday, March 8, 2017, asking for clarification, suggesting a different perspective, remarking on an analysis presented, or suggesting an alternative view. Be sure to formulate a thoughtful and substantive response.

Both Piaget’s Model of Cognitive Development and Kohlberg’s Model of Moral Development are outlined in stages, with one stage building off of the previous stage. Put yourself in the role of parent, teacher and juvenile justice judge and then in each role identify why it would be necessary to understand the cognitive/moral stage from which a child is operating. What are the most important aspects these development models for a parent, teacher and judge to be aware of? Provide examples and be sure to include specific stage characteristics.

 

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Final Paper (Policy)

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PLEASE FOLLOW INSTRUCTIONS CAREFULLY!!! NO POINTS CANT BE DEDUCTED. FOLLOW STEP BY STEP AS INDICATED ABOVE AND DONT MISS ANY. I WILL DISPUTE THE ASSIGNMENT. 

Policy Analysis Paper (30% of final grade) 

 

Due, Sunday, 12/02/17 

Policy Analysis Paper Guidelines 

Purpose: To investigate & integrate knowledge of advanced nursing practice, scholarly inquiry, & leadership by examining a policy at the level of clinical practice, health care systems, or public/social health policy. Students are to submit a paper between 7-10 pages long excluding title page and reference pages. Paper must be organized according to the guidelines below and should include all the identified sections as required. Paper must be completed in APA format and contain current scholarly sources dated from 2010 until current. 

    

Introduction 10 points 

  

▪ Generally define & describe the policy issue to be addressed.
▪ Identify the purpose of analysis, the targeted level of policy (i.e., clinical 

practice, health care systems, or public/social health) & significance of topic. ▪ Identify questions the policy analysis is intended to address. 

   

Background 

10 points 

    ▪  Provide details of the issue or problem, including its nature/scope, relevant literature & history, & the context within which the issue exists.
  ▪  Describe existing policy addressing the issue, if any.
  ▪  Discuss strengths & shortcomings in existing policy.
  ▪  Identify & describe key stakeholders (individuals & groups) that are or will
be affected by the policy & why.
 

   

Analysis 

30 points 

    ▪  Identify alternative policies to achieve objectives.
  ▪  Establish/identify criteria that will be used for selection of “best” policy.
  ▪  Evaluate each alternative & its potential impact relative to the healthcare &
patient outcomes.
  ▪  Assess the trade-offs between alternatives.
 

   

Recommendations 

20 points 

    ▪  Based on the analysis, identify the “best” alternative to address the current issue & policy situation.
  ▪  Provide rationale for selection.
  ▪  Describe possible strategies to implement selected alternative.
  ▪  Identify barriers to implementation of selected alternative.
  ▪  Describe methods to evaluate policy implementation.
 

   

Discussion 20 points 

    ▪  Discuss analysis & recommendations relative to the original questions identified, & the level of policy it is intended to address (i.e., clinical practice, health care systems, or public).
  ▪  Identify limitations of analysis.
  ▪  Discuss implications for practice, education, research, & policy-making.
 

   

Conclusion 5 points 

  

▪ Summarize findings & recommendations of analysis
▪ Identify questions to be addressed in future studies or policy analyses. 

   

References 5 points 

  

▪ List all references cited in paper. Must be completed in APA format. 

   

Appendices 

  

▪ Table displaying results of analysis, including, for example, a list of alternatives & the degree to which each alternative may be most effective. Other tables & appendices as needed to support analysis. 

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