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Peak expiratory flow (PEF)

Question

Peak expiratory flow (PEF) is a measure of a patient’s ability to expel air from the lungs.  Patients with

asthma or other respiratory conditions often have restricted PEF.  The mean PEF for children free of asthma is 306.  An investigator wants to test whether children with chronic bronchitis have restricted PEF.  A sample of 40 children with chronic bronchitis are studied and their mean PEF is 279 with a standard deviation of 71.  Is there statistical evidence of a lower mean PEF in children with chronic bronchitis?  Run the appropriate test at .05. 

1. Calculate Critical Z value:

2. Calculate Computed Z:

3. Based on comparing the critical z value to the computed z value, which of the following is (are) true?

 
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One thousand people are enrolled in a 10 year cohort study

Question

One thousand people are enrolled in a 10 year cohort study. At the start of the study, 100 have diagnosed CVD.

Over the course of the study, 80 people who were free of CVD at baseline develop CVD.

 
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A national survey

Question

A national survey is conducted to assess the association between hypertension and stroke in persons over 75 years

of age with a family history of stroke. Development of stroke is monitored over a 5 year follow-up period. The data is summarized below and the numbers are in millions:

                                  Developed Stroke                  Did Not develop stroke

Hypertension                 24                                                 74

No Hypertension           8                                                  52

1. Compute the cumulative incidence of stroke in persons over 75 years of age

Cumulative Incidence 5 years=

2.Compute the relative risk of stroke in hypertensive as compared to non-hypertensive persons

Relative Risk=

3. Compute the odds ratio of stroke in hypertensive as compared to non-hypertensive persons

Odds Ratio=

 
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serum cholesterol.

Question

An observational study is conducted to investigate the association between age and total serum cholesterol. The

correlation is estimated at r=0.35. The study involves n=125 participants and the mean (std dev) age is 44.3 (10.0) years with an age range of 35-55 years, and mean (std dev) total cholesterol is 202.8 (38.4). The regression equation is below: Y= 143.4+1.34x

Estimate the total serum cholesterol for a 50 year old person

 
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