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A clinical trial

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A clinical trial is being planned to investigate the effect of a new experimental drug designed to reduce total

serum cholesterol.  Investigators will enroll participants with total cholesterol levels between 200-240, they will be randomized to receive the new drug or a placebo and followed for 2 months, and the total cholesterol will be measured.  Investigators plan to run a test of hypothesis and want 80% power to detect a difference of 10 points in mean total cholesterol levels between groups.  They assume that 10% of the participants randomized will be lost over the 2 month follow-up.  How many participants must be enrolled in the study?  Assume that the standard deviation of total cholesterol is 18.5.

 
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is the amount of time Australia children watch television

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is the amount of time Australia children watch television per night less than 196 minutes?

 
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This question was created from Practice Test

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This question was created from Practice Test

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what is the sensitivity of the screening test? What is the false positive fraction of the screening test

 
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MATCH THE FOLLOWING TERMS Prognostic

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MATCH THE FOLLOWING TERMS Prognostic

factor                                              A. Study looking backward in time

Prospective                                                        B. Strongly associated with outcome      

Quasi-experimental                                        C. Subjects assigned to non-overlapping groups

Retrospective                                                    D. Study looking forward in time

Stratification                                                      E. No random assignment           

Question 2

An orthopedic surgeon observes that many of his patients coming in for total knee replacement surgery played organized sports before the age of 10. He plans to collect more extensive data on participation in organized sports from four patients undergoing knee replacement surgery and to report the findings. Identify the type of study proposed and indicate its specific strengths and weaknesses

 
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