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Does the bonding character (and hence the chemical properties) of a compound have much to do with the structure of the nucleus (i.e., how many neutrons)? Or does it have mainly to do with the valence (outer) electrons?

Does the bonding character (and hence the chemical properties) of a compound have much to do

with the structure of the nucleus (i.e., how many neutrons)? Or does it have mainly to do with the valence (outer) electrons?

 
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