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Explain the rationale for the use of hyperthermia in the treatment of cancer.

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a) Explain the rationale for the use of hyperthermia in the treatment of
cancer.
(3 marks)
b) Define the phenomenon of accelerated repopulation during radiation
therapy and list the clinical strategies to overcome this.
(4 marks)
Clinical Radiobiology – Previous Examination Papers
c) Draw a labelled diagram showing tumour control probability (TCP) and
the normal tissue complication probability (NTCP) curves as a function
of total radiation dose. On the same diagram, draw the TCP and NTCP
curves for treatment with concurrent chemo-radiotherapy.

 
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