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Systemic Carnitine

Question

<ol><li>Why will a patient with Systemic Carnitine deficiency experience repeated episodes of

hypoglycemia? </li><li>Why would there be steatosis (lipid accumulation) in th liver of a patient with Systemic Carnitine deficiency? Why will skeletal muscle carnitine content remain below normal despite high-dose carnitine therapy in this patient?</li><li>Give at least 3 possible explanations for a false-negative result in a patient with G6PD deficiency?</li><li>Distinguish in biochemical detail between peroxisomal β-oxidation of fatty acids and mitochondrial β-oxidation of fatty acids.</li><li>Distinguish in biochemical detail between β-oxidation of saturated and unsaturated fatty acids.</li></ol>

 
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