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Which of the following hormones is/are water soluble and therefore bind(s) to extracellular receptors? cortisol epinephrine calcitriol insulin and epinephrine insulin

Which of the following hormones is/are water soluble and therefore bind(s) to extracellular receptors?
cortisol
epinephrine
calcitriol
insulin and epinephrine
insulin

 
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