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Multiple myeloma or blood plasma cancer is characterized by increased blood vessel formulation

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Multiple myeloma or blood plasma cancer is characterized by increased
blood vessel formulation in the bone marrow that is a prognostic factor in survival. One treatment approach used for multiple myeloma is stem cell transplantation with the patient’s own stem cells. The following data represent the bone marrow microvessel density for a sample of 7 patients who had a complete response to a stem cell transplant as measured by blood and urine tests. Two measurements were taken: the first immediately prior to the stem cell transplant, and the second at the time of the complete response.

Patient
1
2
3
4
5
6
7
Before
158
189
202
353
416
426
441
After
284
214
101
227
290
176
290

-Perform an appropriate test of hypothesis to determine if there is evidence, at the .05 level of significance, to support the claim that the mean bone marrow microvessel density is higher before the stem cell transplant than after the stem cell transplant? What is the value of the sample test statistic?
-A. t = 1.8424
–

-B. t = 2.7234
–

-C. z = 1.8424
–

-D. p = 2.7234

 
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