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Which of the following statements is true about Simian Immunodeficiency Virus (SIV)?

Which of the following statements is true about Simian Immunodeficiency Virus (SIV)?

Although SIV has a close relationship to HIV, its inability to infect human tissues demonstrates that SIV is not considered hazardous to humans in the research environment.
The virus occurs naturally in certain species of African monkeys such as the African Green Monkey and the Sooty Mangabey, causing an apparent immunodeficiency syndrome.
Animals infected with SIV must be housed in BSL-1 facilities and handled using BSL-2 procedures as described in the BMBL publication.
SIV has a close relationship to HIV so it has the ability to infect human tissues, and there is evidence of human serologic conversion; thus, SIV should be considered hazardous to humans.

 
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